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KMID : 0608619930030010079
Korean Journal of Aerospace and Environmental Medicine
1993 Volume.3 No. 1 p.79 ~ p.88
An Experimental Study on the Change of EKG in Hyperbaric Oxygenation



Abstract
To estimate the effects of hyperbaric oxygenation on electrocardiographic changes and to estimate the role of hypoxia induced by carbon monoxide poisoning in hyperbaric oxygenation, 20 rabbits were continuously exposed to 4 different conditions ;
1)
breathing ambient air for 30min. followed by 100%-1ATA. Oxygen (AA-NBO group), 2) and by 100%-4ATA. Oxygen (AA-HBO group), 3) breathing carbon monoxide (4,000ppm) for 30 min. followed by 100%-1ATA. Oxygen (CO-NBO group), 4) and by 100%-4ATA.
oxygen
(CO-HBO group). The EKG, the time to dyspnea and convulsion during exposure were recorded and analyzed
Dyspnea was observed in RA-HBO and CO-HBO groups only and the occurrence rates were 80%, 100%, respectively. Convulsion and abnormal EKG findings were observed also in above groups only and the convulsion rates were 20% in both groups and the
rate
of
abnormal EKG findings were 80% in both groups. Death was observed in 2 cases of CO-HBOP group.
Abnormal EKG findings observed were Sinus-bradycardia, T-inversion and ST-T changes (St depression and elevation) in the order and frequency of appearances (p>0.05). Those changes showed a tendency to appear earlier in CO-HBO group than in RA-HBO
group
(p>0.05) when compad by the time of exposure, abnormal EKG findings and dyspnea appeared earlier than dyspnea (p>0.05), former two didn't show any difference in the time of onset.
These results suggest that the principal hazard of hyperoxia of EKG is myocardial ischemia involving ST-T changes and arrhythmia, and that the preceding hypoxic condition may exaggerate the following hyperoxic injury.
KEYWORD
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